Generic Name: Methamphetamine (meth-am-FET-uh-meen) Hydrochloride (HCl)
Brand Name: Desoxyn®
What is Desoxyn®?
Marketed under the brand Desoxyn®, Methamphetamine HCl functions as a central nervous system (CNS) stimulant and has been FDA approved for the treatment of attention deficity hyperactivity disorder in adults and children, as well as for obesity.
Physicians hesitate to prescribe Desoxyn® because of its very high potential for abuse and addiction. It is usually tried out after other stimulants, such as adderall and dexedrine have been tried and failed to work.
How Does Desoxyn® Work?
Although it is not known exactly how Desoxyn® works, it is believed to increase the flow of the neurotransmitters dopamine and norepinephrine, chemicals that carry the signal between neurons (cells of the nervous system). This can result in an increase in a person’s ability to focus over extended periods of time.
Desoxyn® vs Adderall®
Because of its addictiveness, Desoxyn® will normally only be prescribed when Adderall® and other medications have failed to work. Even then, doctors are generally very hesitant to prescribe it. Desoxyn® last longer in one’s system than Adderall® and so one’s last dosage must normally be earlier in the day. It is also thought that Desoxyn® has less effect on the parasympathetic nervous system and causes greater dopamine release than Adderall®.
How Do I Take Desoxyn®?
Methamphetamine HCl comes in tablets of 5 mg each. Normally, patients start with one tablet and day and this is only increased if the medication is not working. The goal is to ensure that the smallest effective dosage is used. This medication is a stimulant and will cause sleep difficulties if taken too late in the day.
Due to the controlled nature of this drug, Desoxyn® is now only available in short acting tablets and is very expensive.
Is Desoxyn® Effective for Adult ADHD?
Desoxyn® has been used to treat ADHD in both adults for many years and several studies have shown it to be an effective treatment.
Desoxyn® Minor Side Effects
Common side effects are similar to those typically associated with the use of stimulants, and include:
· Loss of appetite
· Irritability and Restlessness
· Dry mouth
· Difficulty falling asleep
· Diarrhea or Constipation
· Weight loss
· Upset Stomach
Desoxyn® should be avoid in people with a history of heart problems.
Addiction & Abuse
This medication has been extensively abused and so is subject to control under DEA Schedule II. Tolerance develops to Desoxyn® easily and it one can’t suddenly stop taking it.
Pregnancy Category C
Desoxyn® is a category C drug and as such should not be used by women who are pregnant or may get pregnant.
Like most stimulants, when one stops taking them, it can cause feeling of extreme exhaustion.
Pharmacology of Adult ADHD