Wellbutrin

wellbutrin

By Tammy Preston, MS

Generic Name: Bupropion (bew-PROH-pee-on)

Brand Names: Wellbutrin®, Zyban®, Budeprion®, Aplenzin®, Voxra®

Manufacturers: GlaxoSmithKline Inc.

What is Wellbutrin®?
Wellbutrin® is an antidepressant that has shown promise in helping people with childhood and adult ADHD. Antidepressants are sometimes used in conjuction with stimulants (such as Adderall) or as a standalone treatment for sufferers of adult attention deficit hyperactivity disorder. As well, depression and adult ADHD often coexist, and this medication is useful for people dealing with both issues.

How Does Wellbutrin® Work?
It is not known exactly how Wellbutrin® works, but it is thought that it inhibits the reuptake to norepinephrine and dopamine, which creates feelings of enjoyment and motivation.

How Do I Take Wellbutrin®?
Normally Wellbutrin® XR (extended release) is used as this ensures the medication remains effective all day, as well as reduces incidences of side effects.

Is Wellbutrin® Effective for Adult ADHD?
In a double-blind, placebo-controlled, randomized trial of 40 patients, Wellbutrin® showed a statistically significant effect in improving symptoms of people with adult ADHD.

That being said, Wellbutrin® is normally on tried after stimulants such as Adderall have been tried as stimulants are normally more effective in treating adult ADHD.

Wellbutrin® Side Effects
The biggest side effect of Wellbutrin® is the possibility of seizures. This risk is mitigated by using the lowest possible effective dose.

Pregnancy Category C
Women who are pregnant or may become pregnant should not use Wellbutrin®.

Sources
Wilens, et al. (2001), A Controlled Clinical Trial of Bupropion for Attention Deficit Hyperactivity Disorder in Adults, Am J Psychiatry 2001;158:282-288

Comments

  1. I have been on Adderall for 1 1/2 years now and it has changed my life! I am also taking Lexapro w/it. I did not know that wellbrutrin could possibly work better w/adderall. Anyone have any info or advice? My email is ddaugherty91861@yahoo.com

  2. I am trying Wellbutrin, and in 3 days, I had a terrible taste in my mouth. It has been over 8 weeks now, and it has not subsided. What other similar drugs are there to try??? This is VERY frustrating!

  3. I was on Wellbutrin for depression for 2 days when I started feeling really really down and depressed more than usual. I thought it was just me adjusting to the meds but on the 3rd day I had a horrible panic attack, to the point i thought i was dying. Went to the ER and was immediately taken off of it. It was reacting in a such a way with my body that it was causing my anxiety to go way overboard. Now on Zoloft and klonopin and trazodone. Does nothing for me or my depression or ADHD. Going to a new psych doctor tomorrow who can hopefully get me on the right track. I was diagnosed at age 12 with ADHD and was given strattera, did nothing but turned me into a zombie. I pulled away from friends and family and stayed in my bedroom. Eventually it turned into suicidal thoughts, and when i would address this to my mother and the doctor they gave it no serious thought. So when i would have to take my meds i would sneak and flush them down the toilet. I will never be put on that crap again!!

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  1. […] I have been on Adderall for 1 1/2 years now and it has changed my life! I am also taking Lexapro w/it. I did not know that wellbrutrin could possibly work better w … more… […]

  2. […] Taking Wellbutrin for ADHD in Adults – I am trying Wellbutrin, and in 3 days, I had a terrible taste in my mouth. It has been over 8 weeks now, and it has not subsided. What other similar drugs are there to try??? […]

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